Much below that level, young salmon die from deficiency;[135] much above, they die from toxic excess. For External Use Only. Selenium can be refined from these muds by a number of methods. For treatment of tinea versicolor: Apply to affected areas and lather with a small amount of water. {{#ask: Page Name::Selenium sulfide Selenium also has numerous unstable synthetic isotopes ranging from 64Se to 95Se; the most stable are 75Se with a half-life of 119.78days and 72Se with a half-life of 8.4days. Their use continued into the 1990s. WHEN USED ON BODY SURFACES FOR THE TREATMENT OF TINEA VERSICOLOR, SELENIUM SULFIDE IS CLASSIFIED AS PREGNANCY CATEGORY "C". It is toxic by ingestion and inhalation, and is irritating to skin and eyes. [139], Selenium deficiency, defined by low (<60% of normal) selenoenzyme activity levels in brain and endocrine tissues, occurs only when a low selenium level is linked with an additional stress, such as high exposures to mercury[140] or increased oxidant stress from vitamin E deficiency. Copper indium gallium selenide is a material used in solar cells. Ele usado como agente antifngico em xampus para o tratamento da dermatite seborrica e caspa associadas a fungos do gnero Malassezia. Editor-In-Chief: C. Michael Gibson, M.S., M.D. In high concentrations, selenium acts as an environmental contaminant. Selenium sulfide is a antiseborrheic and dermatological agent that is FDA approved for the treatment of tinea versicolor, seborrheic dermatitis of the scalp, and dandruff. Selenium sulfide is toxic by ingestion and inhalation, and is irritating to skin and eyes. The 1,2 isomer can be prepared by reaction of chlorosulfanes and dichlorodiselane with potassium iodide in carbon disulfide. [71] These detectors use amorphous selenium to capture and convert incident x-ray photons directly into electric charge.[72]. In the Se8 rings, the Se-Se distance varies depending on where the pair of atoms is in the ring, but the average is 233.5 pm, and the Se-Se-Se angle is on average 105.7. A reduction of 21% on TPO antibodies is reported with the dietary intake of 0.2mg of selenium. For this purpose, various selenite and selenate salts are added. [7][8][9], The systemic absorption and toxicity of orally administered selenium sulfide has been studied in animals. Berzelius and Gahn wanted to use the pyrite and they also observed that the red precipitate gave off a smell like horseradish when burned. You need your mouth filled, something long and hard and fleshy sliding between your lips, over your tongue, and down your throat. Except where otherwise noted, data are given for materials in their, Risto S. Laitinen, Pentti Pekone, Yrj Hiltunen and Tapanin A. Pakkanen (1989), "The, Arto Maaninen, Tristram Chivers, Masood Parvez, Jarkko Pietikinen, and Risto S. Laitinen (1999), "Syntheses of THF Solutions of SeX, https://en.wikipedia.org/w/index.php?title=Selenium_hexasulfide&oldid=1034028012, Chemical articles with multiple compound IDs, Chemical articles with multiple PubChem CIDs, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Short description is different from Wikidata, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 17 July 2021, at 10:18. For the software testing framework, see, Chemical element, symbol Se and atomic number 34, A Se(0) atom has been identified using DFT in [ReOSe(2-pySe). It has an approximate composition of SeS2, with individual rings varying in composition, such as Se4S4 and Se2S6. WebSelenium sulfide also referred to as Selenium disulfide is a liquid antiseborrheic and antifungal preparation that should only be used topically. )[100], Selenium may inhibit Hashimoto's disease, in which the body's own thyroid cells are attacked as foreign. Hazards What is this information? Twenty male patients with a diagnosis of tinea versicolor were randomly assigned to two parallel groups who applied selenium sulfide lotion or the vehicle to the entire skin surface, excluding mucous membranes, fo The isomer n-butane can connect in two ways, giving rise to two "-butyl" groups: . arrow-right-small-blue [6], Selenium forms several allotropes that interconvert with temperature changes, depending somewhat on the rate of temperature change. [124], Although selenium is an essential trace element, it is toxic if taken in excess. Analysis of blood levels of inorganic compounds in the supplement indicated the selenium concentrations were 10 to 15 times higher than normal in the blood samples, and 15 to 20 times higher than normal in the liver samples. Selenium enzymes are involved in the small reducing molecules glutathione and thioredoxin. See application instructions on rear panel of this bottle. There is limited information regarding Monitoring of Selenium sulfide in the drug label. [2][3]It is applied to the Lucas Entertainment entered the bareback arena in 2013 with its Cybersocket Award Winner Spotlight: Rhyheim Shabazz, Top Cock of the Year, Pumping Up With AJ Sloan: Get It Wet Hydration Tips for Thirsty Guys, Where Are They Now: Trevor Knight Talks His 10-Inch Dick, His Studios Days as a Porn God, & Coming Back on OnlyFans, 7 Sexy Questions (VIDEO): Trent Marx Talks Gay Porn, Fav Sex Positions & Accidental Consent, Family Dick Serves Up a Hearty Twink Sandwich With Derek Allen As the Main Meat, Cybersocket Exclusive Interview: Ring in the Holidays With Tom Goss New EP Big Gay Ass Christmas, Young Bastards Has an Oral Scene So Hot You Wont Miss the Anal, Doctor Tapes: Cute Myott Hunter Reveals Ive Got the Hots For Doc Dalton Riley. There are, however, a few species that have been seen to survive these events and tolerate the increased selenium. This smell was not typical of arsenic, but a similar odor was known from tellurium compounds. We all appreciate getting nice and sweaty at the gym, but what comes out must be put back in. [20][19], Side effects of selenium disulfide shampoo for dandruff appear to be infrequent. Jump search Mixture selenium sulfides.mw parser output .infobox subbox padding border none margin 3px width auto min width 100 font size 100 clear none float none background color [11][12][13] It is also used on the body to treat tinea versicolor (pityriasis versicolor), a type of fungal skin infection caused by a different species of Malassezia. [87] Fish are a major source of protein for humans, people who eat more fish are generally healthier than those who eat less, indicating selenium pollution does not appear to be a problem, although it might be useful to be aware that selenium has a potential effect on humans. Selenium Sulfide Topical Suspension USP, 2.5% (Lotion) is available as follows: 4 fl oz plastic bottle (NDC 45802-040-64). In addition to controlling the symptoms [24][7] Topical use of selenium sulfide in the form of a shampoo or lotion in humans does not appear to normally increase circulating or urinary selenium levels. In plants, it occurs as a bystander mineral,[95] sometimes in toxic proportions in forage (some plants may accumulate selenium as a defense against being eaten by animals,[96] but other plants, such as locoweed, require selenium, and their growth indicates the presence of selenium in soil).[97]. [61][63], The largest commercial use of Se, accounting for about 50% of consumption, is for the production of glass. This product should not be used by patients allergic to any of its components. In fact, the angiosperms (the dominant type of plant today) and most of their antioxidant pigments evolved during the late Jurassic period. [105] Evidence suggests that the molecular mechanisms of mercury toxicity includes the irreversible inhibition of selenoenzymes that are required to prevent and reverse oxidative damage in brain and endocrine tissues. [2] Selenium disulfide appears to be much less toxic than other selenium salts, which may be attributed to its low aqueous solubility and very poor systemic absorption. There is limited information regarding FDA-Labeled Use of Selenium sulfide in pediatric patients. From about 500 million years ago, freshwater and terrestrial plants slowly optimized the production of "new" endogenous antioxidants such as ascorbic acid (vitamin C), polyphenols (including flavonoids), tocopherols, etc. There is no FDA guidance on the use of Selenium sulfide with respect to nursing mothers. There is no FDA guidance on use of Selenium sulfide during labor and delivery. Its molecular structure consists of a ring of two selenium and six sulfur atoms, analogous to the S8 allotrope of sulfur (cyclooctasulfur) and other selenium sulfides with formula SenS8n.[2]. There have been no documented reports of serious toxicity in humans resulting from acute ingestion of Selenium Sulfide Topical Suspension USP, 2.5% (Lotion); however, acute toxicity studies in animals suggest that ingestion of large amounts could result in potential human toxicity. [15][16] Based on the study, the systematic review concluded that selenium disulfide may be effective in the treatment of dandruff but that the available evidence is limited and overall evidence quality is low. Selenium sulfide topical (for the skin) is used to treat dandruff, seborrhea, and tinea Selenium sulfides are a group of 8 memebered ring compounds, with the general formula Se8-n Sn. Brazil nuts are the richest dietary source (though this is soil-dependent, since the Brazil nut does not require high levels of the element for its own needs).[119][120]. [2][3] It is applied to the affected area as a lotion or shampoo. [1][4] Use in pregnancy or breastfeeding has not been studied. Selenium requirements in plants differ by species, with some plants requiring relatively large amounts and others apparently not requiring any. Gray Se is formed by mild heating of other allotropes, by slow cooling of molten Se, or by condensing Se vapor just below the melting point. Some commonly used brand names are Selsun, Exsel and Head and Shoulders Intensive Treatment. Reproduction of mallard ducks is impaired at dietary concentrations of 7g Se/L. The new brass is marketed under the name EnviroBrass. [37], Cyclic selenium sulfides R. Steudel, R. Laitinen, Topics in Current Chemistry, (1982), 102, 177-197, Srpskohrvatski / , World Health Organization's List of Essential Medicines, "Selenium sulfide topical Use During Pregnancy", Selenium(IV) sulfide - pharmacy codes search engine, "Meibomian Gland Dysfunction: A Dermatological Perspective on Pathogenesis and Treatment Outlook", "Zur Resorption und Toxicitt von Selensulfid", "Definition: selenium sulfide from Online Medical Dictionary", "Topical Selenium Sulfide for the Treatment of Hyperkeratosis", "ARVO 2021: Investigational Agent Containing Selenium Sulfide Shows Promise for Meibomian Gland Dysfunction", "A randomized, double-blind, placebo-controlled trial of ketoconazole 2% shampoo versus selenium sulfide 2.5% shampoo in the treatment of moderate to severe dandruff", https://en.wikipedia.org/w/index.php?title=Selenium_disulfide&oldid=1108463362, World Health Organization essential medicines, Infobox drug articles without a structure image, Articles containing unverified chemical infoboxes, Wikipedia medicine articles ready to translate, Creative Commons Attribution-ShareAlike License 3.0, 118 to 119C (244 to 246F) (decomposes), This page was last edited on 4 September 2022, at 14:56. Selenium sulfide. Cookies help us deliver our services. A selenide is a chemical compound containing a selenium anion with oxidation number of 2 (Se 2 ), much as sulfur does in a sulfide. Another naturally occurring organoselenium compound is dimethyl selenide. It is also used [80] In X-ray crystallography, incorporation of one or more selenium atoms in place of sulfur helps with multiple-wavelength anomalous dispersion and single wavelength anomalous dispersion phasing. If you have any concerns with your skin or its treatment, see a dermatologist for advice. The minimum distance between chains is 343.6pm. The selenocysteine-containing form occurs in species as diverse as green algae, diatoms, sea urchins, fish, and chickens. [133], In fish and other wildlife, selenium is necessary for life, but toxic in high doses. There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Selenium sulfide in women who are pregnant. COMMON BRAND NAME (S): Exsel, Tersi Foam SHAKE WELL BEFORE USING. Hence, Berzelius's first letter to Alexander Marcet stated that this was a tellurium compound. Selenium intensifies and extends the tonal range of black-and-white photographic images and improves the permanence of prints. [35][36][37] The development of selenium rectifiers began during the early 1930s, and these replaced copper oxide rectifiers because they were more efficient. The contents of this FDA label are provided by the National Library of Medicine. There is no FDA guidance on the use of Selenium sulfide in patients with renal impairment. Selenium sulfide is a bright orange colored powder. [35] It has also been reported to be effective in the treatment of scalp psoriasis based on clinical observation of over 100treated patients and two case reports of dramatic response. [6] Selenium disulfide acts as a keratolytic and antifungal agent. (Only the deiodinase iodotyrosine deiodinase, which works on the last breakdown products of thyroid hormone, does not use selenium. A liquid antiseborrheic, antifungal preparation for topical application. [47][48], In living systems, selenium is found in the amino acids selenomethionine, selenocysteine, and methylselenocysteine. [25][26][27][28][29] However, application of selenium disulfide to damaged skin can result in systemic absorption and has been associated with cases of toxicity. Avoid getting shampoo in eyes or in contact with genital area as it may cause irritation and burning. Drug Information: Selenium Sulfide (Topical), Apply enough selenium sulfide shampoo to the scalp to, Allow lather to remain on scalp for 2-3 minutes before rinsing off, Repeat with a second wash then rinse well, Use 1% or 2.5% shampoo twice a week for the first 2 weeks, then once weekly for 2, 3 or 4 weeks, and then only when necessary, Apply selenium sulfide lotion to affected areas of the body (do not apply to face or genitals), Work up a lather using a small amount of water, Allow the medicine to stay in contact with your skin for about 10 minutes, Rinse body well to remove all the medicine, Use the 2.5% lotion once per day for 7 days, Unusual oiliness or dryness of hair or scalp. There is no FDA guidance on the use of Selenium sulfide with respect to geriatric patients. various regions within North America) where low selenium soil levels lead to low concentrations in the plants, some animal species may be deficient unless selenium is supplemented with diet or injection. These findings suggest that, with the exception of vertebrates, aquatic life supports selenium use, whereas terrestrial habitats lead to reduced use of this trace element. |?Pill Dosage This process leaches natural soluble selenium compounds (such as selenates) into the water, which may then be concentrated in wetlands as the water evaporates. FDA-Labeled Indications and Dosage (Adult), FDA-Labeled Indications and Dosage (Pediatric), Females of Reproductive Potential and Males. |?NDC [7], Selenium disulfide has a composition that approximates to SeS2 and is sometimes called selenium sulfide. Whereas other Se forms are insulators, gray Se is a semiconductor showing appreciable photoconductivity. [4], Side effects may include hair discoloration, skin irritation, and risk of systemic absorption and toxicity, among others. [148], The effects of selenium intake on cancer have been studied in several clinical trials and epidemiologic studies in humans. It is a nonmetal (more rarely considered a metalloid) with properties that are intermediate between the elements above and below in the periodic table, sulfur and tellurium, and also has similarities to arsenic. Author: Vanessa Ngan, Staff Writer, 2005. Store at 20-25C (68-77F) [see USP Controlled Room Temperature]. These data exclude two major producers: the United States and China. In 1873, Willoughby Smith found that the electrical resistance of grey selenium was dependent on the ambient light. Selenium has seven naturally occurring isotopes. In June 2015, the US Food and Drug Administration (FDA) published its final rule establishing the requirement of minimum and maximum levels of selenium in infant formula. WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. |?Pill Imprint Gu thng [149] However, in a case of combined iodine and selenium deficiency, selenium deficiency was shown to play a thyroid-protecting role. [3], World Health Organization's List of Essential Medicines. Se compounds confer a red color to glass. In Belews Lake North Carolina, 19 species of fish were eliminated from the lake due to 150200g Se/L wastewater discharged from 1974 to 1986 from a Duke Energy coal-fired power plant. [7][8][9], Selenium disulfide was approved for medical use in the United States at least as early as 1951. Occupational Safety and Health Administration, National Institute for Occupational Safety and Health, Magnetic susceptibility of the elements and inorganic compounds, "The NUBASE2016 evaluation of nuclear properties", "Lettre de M. Berzelius M. Berthollet sur deux mtaux nouveaux", "Effect of light on selenium during the passage of an electric current", "The need for selenite and molybdate in the formation of formic dehydrogenase by members of the Coli-aerogenes group of bacteria", "How Selenium Has Altered Our Understanding of the Genetic Code", 10.1579/0044-7447(2007)36[94:SGAH]2.0.CO;2, "How to use the world's scarce selenium resources efficiently to increase the selenium concentration in food", "Public Health Statement: Selenium Production, Import/Export, Use, and Disposal", "Chemistry: Periodic Table: selenium: key information", "Selenium and Tellurium: Statistics and Information", "Radiography of Welds Using Selenium 75, Ir 192 and X-rays", "Aquatic selenium pollution is a global environmental safety issue", "Mercury, selenium and fish oils in marine food webs and implications for human health", "Review of selenium toxicity in the aquatic food chain", "A teratogenic deformity index for evaluating impacts of selenium on fish populations", "Selenium accumulation protects plants from herbivory by Orthoptera via toxicity and deterrence", "Selenium concentrations in leaf material from Astragalus Oxyphysus (diablo locoweed) and Atriplex Lentiformis (quail bush) in the interior Coast Ranges and the western San Joaquin Valley, California", Linus Pauling Institute at Oregon State University, "Effect of Selenium on Thyroid Disorders: Scientometric Analysis", "Dietary and tissue selenium in relation to methylmercury toxicity", "Post-transcriptional defects of antioxidant selenoenzymes cause oxidative stress under methylmercury exposure", "Protective effect of selenite against methylmercury toxicity: observations concerning time, dose and route factors in the development of selenium attenuation", "Inhibition of the human thioredoxin system: A molecular mechanism of mercury toxicity", Strong antioxidant activity of the novel selenium-containing imidazole compound selenoneine, "Discovery of the strong antioxidant selenoneine in tuna and selenium redox metabolism", "Mercury: selenium interactions and health implications", "Selenocysteine-containing proteins in mammals", "Evolutionary dynamics of eukaryotic selenoproteomes: large selenoproteomes may associate with aquatic life and small with terrestrial life", "Evolution of Dietary Antioxidant Defences", "Reconsidering the evolution of eukaryotic selenoproteins: a novel nonmammalian family with scattered phylogenetic distribution", "The microbial selenoproteome of the Sargasso Sea", "FDA Issues Final Rule to Add Selenium to List of Required Nutrients for Infant Formula", "Selenium stimulates the antitumour immunity: Insights to future research", "Dietary Supplement Fact Sheet: Selenium", "Public Health Statement: Health Effects", "Polo pony selenium levels up to 20 times higher than normal", "CDC NIOSH Pocket Guide to Chemical Hazards Selenium", "Effect of micronutrient status on natural killer cell immune function in healthy free-living subjects aged 90 y", "Selenium and iodine supplementation of rural Tibetan children affected by Kashin-Beck osteoarthropathy", "Serum Selenium Status and Its Interrelationship with Serum Biomarkers of Thyroid Function and Antioxidant Defense in Hashimoto's Thyroiditis", "Selenium deficiency mitigates hypothyroxinemia in iodine-deficient subjects", National Institutes of Health page on Selenium, CDC NIOSH Pocket Guide to Chemical Hazards, https://en.wikipedia.org/w/index.php?title=Selenium&oldid=1123158494, Chemical elements with trigonal structure, Articles with dead external links from November 2020, Short description is different from Wikidata, Articles containing Swedish-language text, Articles to be expanded from February 2022, Articles with unsourced statements from June 2016, Pages using Sister project links with hidden wikidata, Creative Commons Attribution-ShareAlike License 3.0, grey metallic-looking, red, and vitreous black (not pictured) allotropes, This page was last edited on 22 November 2022, at 06:06. [58], Industrial production of selenium usually involves the extraction of selenium dioxide from residues obtained during the purification of copper. }}, Selenium Sulfide Topical Suspension USP, 2.5% (Lotion), {{#ask: Label Page::Selenium sulfide It is recommended that a water concentration of 2g Se/L be considered highly hazardous to sensitive fish and aquatic birds. Selenium sulfide has the molecular formula SeS2 and has a molecular weight of 143.09. 2. A vdjegyzett ksztmnyek azonban nem egyetlen tiszta vegyletet tartalmaznak, hanem olyan keverket, melyben az Se:S arny sszessgben 1:2. WebSulfeto de selnio ( portugus brasileiro) ou sulfeto de selnio ( portugus europeu) (mais precisamente dissulfeto de selnio ou sulfeto de selnio (IV)) o composto de frmula qumica SeS 2 . [2], Selenium disulfide acts as an antifungal and keratolytic agent to treat seborrheic dermatitis and dandruff. Scientific Facts: Selenium is a naturally occurring mineral element found in rocks and soil. Do not leave on hair, scalp or skin for periods longer than directed and ensure all selenium sulfide is rinsed off well. [15] It also found that while selenium disulfide has infrequent side effects, it seems to have more side effects than ketoconazole shampoo. |template=DrugPageImages This page was last edited 17:24, 5 February 2015 by wikidoc user. This one does too, but it a really good way like in a two boxes of Kleenex way. [122], Certain species of plants are considered indicators of high selenium content of the soil because they require high levels of selenium to thrive. Selenoprotein families of GSH-Px and the deiodinases of eukaryotic cells seem to have a bacterial phylogenetic origin. Another source was the mud from the lead chambers of sulfuric acid plants, a process that is no longer used. In nature, Selenium is usually combined with sulfide. It seldom occurs in its elemental state or as pure ore compounds in the Earth's crust. Selenium was also recognized as an important veterinary toxin, which is seen in animals that have eaten high-selenium plants. WebSelenium is a chemical element with the symbol Se and atomic number 34. [8] It resists oxidation by air and is not attacked by nonoxidizing acids. The US Recommended Dietary Allowance (RDA) of selenium for teenagers and adults is 55g/day. Selenium transmits an electric current proportional to the amount of light falling on its surface. Selenium poisoning can be passed from parents to offspring through the egg, and selenium poisoning may persist for many generations. There is no FDA guidance on the use of Selenium sulfide with respect to specific gender populations. WebSELENIUM SULFIDE (se LEE nee um suhl fahyd) skin lotion is used to treat dandruff-like conditions, seborrhea, and psoriasis. [8], The red , , and forms are produced from solutions of black selenium by varying the evaporation rate of the solvent (usually CS2). Selenium from Dermatology Made Easybook. Other problems include degeneration of liver tissue, swelling around the heart, damaged egg follicles in ovaries, cataracts, and accumulation of fluid in the body cavity and head. [36], Selenium sulfide is under development for the treatment of meibomianitis (meibomian gland dysfunction) and dry eyes in topical and ophthalmic formulations. Selen disulfide l mt loi thuc c s dng iu tr chng au tht ngc, vim da tit b v gu. [30], Many selenium sulfides are known, as indicated by 77Se-NMR spectroscopy. [54], Selenium is most commonly produced from selenide in many sulfide ores, such as those of copper, nickel, or lead. [145] Ruminants grazing certain forages, e.g., some white clover varieties containing cyanogenic glycosides, may have higher selenium requirements,[145] presumably because cyanide is released from the aglycone by glucosidase activity in the rumen[146] and glutathione peroxidases is deactivated by the cyanide acting on the glutathione moiety. 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