The groom is a son of Sue and Andy McMaster of Darien. Research in the Miller Laboratory is divided into three main areas of focus: Innate & Adaptive Immunity All rights Reserved. Matthew Miller PhD Faculty Full Biography Associate Professor, Scientific Director, Michael G. DeGroote Institute for Infectious Disease Research (IIDR) Scientific Director, Michael G. DeGroote Institute for Infectious Disease Research (IIDR) Biochemistry and Biomedical Sciences, McMaster Immunology Research Centre More than 400 graduate students, post-doctoral and clinical fellows research various programs funded by provinci . Henry Dargan McMaster (born May 27, 1947) is an American politician and attorney serving as the 117th governor of South Carolina since January 24, 2017. He attended Hobart College and received his master's from Syracuse University. Indeed, where Wrights focus has largely orbited around antimicrobial resistance (AMR), Miller specializes in viral pandemics, including those caused by influenza and SARS-CoV-2. The Miller group is focused on understanding the immunobiology of these antibodies, how they are elicited, and how they may be useful for the generation of universal influenza virus vaccines and therapeutics. At the top of the Mcmaster . The Faculty of Health Sciences is committed to providing a website that is accessible to the widest possible audience. McMaster Design Agency. AMR will always be a central priority for the IIDR, not only because it is one of the most important global health challenges of our time, but also because the international profile of the IIDR has, to a large extent, been built on the back of our success in AMR research, he explains. Upon infection, both the innate and adaptive immune system is mobilized to protect the host from virus-mediated pathologies. The virus has specific properties that allow it to cause seasonal epidemics and periodic pandemics, which leads to current- generation IAV vaccines having to be administered seasonally, while providing optimal protection against only a very limited number of IAV strains. "Matthew Miller is an outstanding scientist and person, and his important research like that into next-generation COVID-19 vaccines will no doubt propel the IIDR to new heights," says Wright, who stepped down from his post at the IIDR to focus on establishing Canada's Global Nexus for Pandemics and Biological Threats. Dr. Matthew Miller is an assistant professor in the Department of Biochemistry and Biomedical Sciences at Mcmaster University, and principal investigator in The Institute for Infectious Diseases Research and The Mcmaster Immunology Research Centre. Matthew S Miller Associate Professor, Biochemistry & Biomedical Sciences The Miller Laboratory studies diverse aspects of virus-host interactions. Copyright 2020 McMaster University. Original article posted on brighterworld.mcmaster.ca on November 6, 2020 (Photo by Matt Clarke/McMaster University). High-dose dexamethasone compared with prednisone for previously untreated primary immune thrombocytopenia: a systematic review and meta-analysis. ALS Through the Nexus, Wright will remain a key collaborator for the IIDR a partnership Miller believes will create immense opportunity for the Institute. Assistant Dean, Biochemistry Graduate Program. The Miller Laboratory is studying strategies to prevent vaccine resistance by targeting conserved features of the . HERE are many translated example sentences containing "DR MATTHEW MILLER" - french-english translations and search engine for french translations. That said, we cannot rest on our laurels. McMaster University, Hamilton, Ontario, Canada Date Created: Thu Jun 24 00:00:00 EDT 2021 . We asked Matthew Miller, associate professor, biochemistry and biomedical sciences, to answer questions from our community about COVID-19, pandemics, and infectious diseases in general. Rapid Design of a Bait Capture Platform for Culture- and Amplification-Free Next-Generation Sequencing of SARS-CoV-2, Thermal Stabilization of Viral Vaccines in Low-Cost Sugar Films, Correction to: Determinants of Influenza Mortality Trends: Age-Period-Cohort Analysis of Influenza Mortality in the United States, 19592016, Determinants of Influenza Mortality Trends: Age-Period-Cohort Analysis of Influenza Mortality in the United States, 19592016, Comparative Immunogenicity of the 20142015 Northern Hemisphere Trivalent IIV and LAIV against Influenza A Viruses in Children, Excipient selection for thermally stable enveloped and non-enveloped viral vaccine platforms in dry powders, Original Antigenic Sin: How First Exposure Shapes Lifelong AntiInfluenza Virus Immune Responses, Reporting and evaluating influenza virus surveillance data: An argument for incidence by single year of age, Reviewing the evidence for viruses as environmental risk factors for ALS: A new perspective, Gnothi Seauton: Leveraging the Host Response to Improve Influenza Virus Vaccine Efficacy, Pandemic Paradox: Early Life H2N2 Pandemic Influenza Infection Enhanced Susceptibility to Death during the 2009 H1N1 Pandemic, Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice, Regulation of kynurenine biosynthesis during influenza virus infection, Abnormal regulation of the antiviral response in neurological/neurodegenerative diseases, Broadly Neutralizing Hemagglutinin Stalk-Specific Antibodies Induce Potent Phagocytosis of Immune Complexes by Neutrophils in an Fc-Dependent Manner, Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus, Optimal activation of Fc-mediated effector functions by influenza virus hemagglutinin antibodies requires two points of contact, Hemagglutinin Stalk Immunity Reduces Influenza Virus Replication and Transmission in Ferrets, CARMA3 Is a Host Factor Regulating the Balance of Inflammatory and Antiviral Responses against Viral Infection, Measuring the neutralization potency of influenza A virus hemagglutinin stalk/stem-binding antibodies in polyclonal preparations by microneutralization assay, Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis, Broadly Neutralizing Anti-Influenza Virus Antibodies: Enhancement of Neutralizing Potency in Polyclonal Mixtures and IgA Backbones, Is Antigenic Sin Always Original? Re-examining the Evidence Regarding Circulation of a Human H1 Influenza Virus Immediately Prior to the 1918 Spanish Flu, Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans, Peering into the Crystal Ball: Influenza Pandemics and Vaccine Efficacy, Assessment of Influenza Virus Hemagglutinin Stalk-Based Immunity in Ferrets, Neutralizing Antibodies Against Previously Encountered Influenza Virus Strains Increase over Time: A Longitudinal Analysis, Serum- and Glucocorticoid-Regulated Kinase 1 Is Required for Nuclear Export of the Ribonucleoprotein of Influenza A Virus, 1976 and 2009 H1N1 Influenza Virus Vaccines Boost Anti-Hemagglutinin Stalk Antibodies in Humans, Age-Specific Mortality During the 1918 Influenza Pandemic: Unravelling the Mystery of High Young Adult Mortality, Characterization of the 55-Residue Protein Encoded by the 9S E1A mRNA of Species C Adenovirus, Adenovirus E1A Directly Targets the E2F/DP-1 Complex, An unhealthy relationship: viral manipulation of the nuclear receptor superfamily, RASCAL Is a New Human Cytomegalovirus-Encoded Protein That Localizes to the Nuclear Lamina and in Cytoplasmic Vesicles at Late Times Postinfection, Onset of Human Cytomegalovirus Replication in Fibroblasts Requires the Presence of an Intact Vimentin Cytoskeleton, Human cytomegalovirus US9 protein contains an N-terminal signal sequence and a C-terminal mitochondrial localization domain, and does not alter cellular sensitivity to apoptosis, Antibody idiotype plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity (ADCC) against influenza A virus, Fc-dependent effector functions of neutrophils induced by hemagglutinin stalk-specific antibodies, Road to Biomedical Discovery - BIOMEDDC 3A03, Drug Discovery and Development - BIOMEDDC 3B06B, Drug Discovery and Development - BIOMEDDC 3B06A, Independent Study in Medical Sciences - MEDSCI 799. Current areas of focus include: Associate Professor, Biochemistry & Biomedical Sciences, McMaster Immunology Research Centre (MIRC), Michael G. DeGroote Institute for Infectious Disease Research (IIDR). It is bittersweet moving on, but knowing that Matthew is stepping in fills me with great confidence and great pride.. Part of being an innovative and world-leading institute is evolving and being forward-looking, and I believe that my experience studying virology and viral pandemics will allow us to advance new priority research areas for the Institute going forward, as we continue to support our core strength in AMR.. Influenza A virus (IAV) presents a particularly formidable challenge to the adaptive immune system. Matthew Miller Description: Portrait of Matthew Miller, Assistant Dean - Biochemistry Graduate Program, The Miller Laboratory, Associate . As a postdoctoral fellow, I trained in viral immunology, focused primarily on pandemic influenza and vaccinology. 1280 Main Street West, Room 2235 | Hamilton, Ontario | L8S 4L8. Mortality trends during influenza virus pandemics Dr. Matthew Miller Far from suffering any negative consequences from this outrageous statement, which was literally a call for rigid social isolation of the unjabbed, Miller is still being. 15/2022), Inactivated and live-attenuated seasonal influenza vaccines boost broadly neutralizing antibodies in children, Gut microbiota-based vaccination engages innate immunity to improve blood glucose control in obese mice, Lasting Changes to Circulating Leukocytes in People with Mild SARS-CoV-2 Infections, HighAffinity Dimeric Aptamers Enable the Rapid Electrochemical Detection of WildType and B.1.1.7 SARSCoV2 in Unprocessed Saliva, Probe design for simultaneous, targeted capture of diverse metagenomic targets, Antibody Responses 3-5 Months Post-Vaccination with mRNA-1273 or BNT163b2 in Nursing Home Residents, Effects of repeated vaccination and vaccine formulation on the induction of broadly neutralizing antibody responses against influenza A virus in children, Diverse high-affinity DNA aptamers for wild-type and B.1.1.7 SARS-CoV-2 spike proteins from a pre-structured DNA library, IgA potentiates NETosis in response to viral infection, Neutrophils and Influenza: A Thin Line between Helpful and Harmful, A liposome-displayed hemagglutinin vaccine platform protects mice and ferrets from heterologous influenza virus challenge, Covalent Stabilization of Antibody Recruitment Enhances Immune Recognition of Cancer Targets, Experimental and natural evidence of SARS-CoV-2-infection-induced activation of type I interferon responses, Characteristics of Anti-SARS-CoV-2 Antibodies in Recovered COVID-19 Subjects, Engineered Nanoparticle Applications for Recombinant Influenza Vaccines, Predicting the recombination potential of severe acute respiratory syndrome coronavirus 2 and Middle East respiratory syndrome coronavirus, Age-Specific Incidence of Influenza A Responds to Change in Virus Subtype Dominance, Cross-Sectional Evaluation of Humoral Responses against SARS-CoV-2 Spike, Immunological considerations for COVID-19 vaccine strategies, Bat Influenza Viruses: Making a Double Agent of MHC Class II, Isolation, Sequence, Infectivity, and Replication Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2. Abnormal inflammation is a signature of many neurodegenerative diseases, yet the way in which inflammation contributes to the pathology of these diseases is poorly defined. BY Michelle Donovan August 16, 2022 Health & Medicine Infectious Disease Dr. Miller is an Associate Professor in the Department of Biochemistry and Biomedical Sciences at McMaster University. Associate Professor, Department of Biochemistry and Biomedical Sciences Assistant Dean and Associate Chair, Biochemistry Graduate Program. Dr. Miller recently discussed his work on the Bill Kelly Show, CHML 900 Global Radio. Current areas of focus include: 1. Matthew Miller Research in the Miller Laboratory is divided into three main areas of focus: Innate & Adaptive Immunity Upon infection, both the innate and adaptive immune system is mobilized to protect the host from virus-mediated pathologies. In the context of infections caused by viruses like influenza or SARS-CoV-2, it tends to be when the virus gets deep into the lung that it makes you really sick," explains Matthew Miller, a. Jan 2021 - Present1 year 11 months. This Q and A was originally posted as an "Ask Me Anything" series on McMaster's Instagram account. Wright, too, believes that Millers unique expertise will only serve to strengthen the IIDRs research profile. These studies were supported, in part, by a prestigious CIHR Postdoctoral Research Award. Matthew Miller is an outstanding scientist and person, and his important research like that into next-generation COVID-19 vaccines will no doubt propel the IIDR to new heights, says Wright, who stepped down from his post at the IIDR to focus on establishing Canadas Global Nexus for Pandemics and Biological Threats. Startup creative design agency committed to bringing bright ideas to life. Tel: 905-525-9140 ext. Matthew Miller MD, MSc, FRCPC Medicine, Nephrology Associate Professor Director, Nephrology Fellowship Program; Director, Medical Foundations 2; Medical Lead for Living Kidney Donor Program matthew.miller@medportal.ca MacExperts Amber Molnar Medicine, Nephrology Associate Professor 905-521-2100 ext. He works at Mark Finlay Architects. 1280 Main Street West, Room 2235 | Hamilton, Ontario | L8S 4L8. . Matthew McMaster. Eur. In the context of infections caused by viruses like influenza or SARS-CoV-2, it tends to be when the virus gets deep into the lung that it makes you really sick," explains Matthew Miller, a co-author of the study who holds the Canada Research Chair in Viral Pandemics at McMaster University. Matthew S Miller Associate Professor, Department of Biochemistry and Biomedical Sciences, McMaster University Verified email at mcmaster.ca Virology Immunology Microbiology Infectious. In his most recent publication, infectious disease expert Dr. Matthew Miller and colleagues find that being born during influenza pandemics enhances the risk of death during later pandemics. As an independent investigator, my expertise is primarily in the area of viral. During his time in New York, Dr. Millers research focused on characterizing the innate and adaptive immune responses to viral infection. Matthew Miller, director of McMaster's Michael G. DeGroote Institute for Infectious Disease Research, says better strategies are needed to protect people from flu pandemics. Distribution Associate at McMaster-Carr Lansdale, PA. Laura Szczepaniak (Wood) VP Travel Operations at . Matthew Miller, senior author of the paper, an assistant professor of biochemistry and biomedical sciences at McMaster University, and senior researcher with its Michael G. DeGroote Institute of . Influenza virus and the biology of broadly-neutralizing antibodies 2. Matthew Miller, PhD. Dr. Millers interest in infectious diseases and immunology began during his undergraduate education in the BMSc program at the University of Western Ontario, where he completed an Honors Specialization in Microbiology and Immunology. According to the document, Mcmaster University's 1,203 staffers made the Sunshine List, earning total compensation of in 2017. Matt's passion for architectural design emerged while attending Hobart College where he pursued a major in architectural studies and a minor in art history. Repeated Seasonal Influenza Vaccination: How Much Is Too Much of a Good Thing? While Miller says he and Wright already share lot of similarities in style and approach, he acknowledges that their research interests differ considerably. Every year, the Ontario government publishes its annual Sunshine List of public sector servants with six-figure salaries. Call Matthew D. McMaster, LLC now at 800-890-3981 to learn more about Lawyer in Marietta, GA. If there is an accessibility issue with this website, please contact us at fhsaoda@mcmaster.ca. Being named scientific director has been a full-circle experience for Miller, who notes that it was actually the opportunity to work within the IIDR that attracted him to working at McMaster all those years ago. We sit down with Dr. Miller to learn more about the global implications of these findings, what important steps his team at McMaster is taking next, and how the development of a novel universal flu vaccine . This relationship between infection-inflammation-neurodegeneration is an area of active investigation by the Miller Lab. McMaster Biochemistry and Biomedical Sciences Society, Biomedical Discovery and Commercialization, Microbiology, Immunology and Drug Discovery, Biophotonics Laboratory for Microscopy and Molecular Imaging, Institute for Infectious Disease Research, Farncombe Family Digestive Health Research Institute, Centre for Metabolism, Obesity, and Diabetes Research, Postdoctoral Affairs and Research Training, Equipment, Room Booking & Supply Ordering. Canadian researcher Matthew Miller believes that could happen with a decade. All rights Reserved. 1280 Main Street West, Room 2235 | Hamilton, Ontario | L8S 4L8. He was also honored to receive the Dr. John Robinson Graduate Scholarship, the John A. Thomas Award and the Stephen D. Poland Award from the Department of Microbiology and Immunology at Western University. Photography: Bruce Plotkin Photography Jeanne Ladue with Lindsey Floral centerpiece Executed projects for large . As a small liberal arts college, Matt was able to develop a strong architectural skill set while also pursuing a variety of other subjects linked closely to the . The Miller Laboratory studies diverse aspects of virus-host interactions. Influenza Virus Matthew Miller Associate Professor, Medicine Contact Information EMAIL: millemc Affiliations Faculty of Health Sciences, McMaster University Associate Professor, Medicine, Faculty of Health Sciences Scholarly Activity in McMaster Experts Co-author Network Scholarly Activity Contact View All selected scholarly activity academic article Copyright 2020 McMaster University. Dr. Dr. Miller also discovered an unexpected role for Senataxin a protein involved in several neurodegenerative disorders, including ALS in regulating the antiviral response. Miller, a long-time member of the IIDR, transitioned into his new role on July 18, 2022, marking the first time that the Institute has been under new leadership since Gerry Wright served as its inaugural director upon its establishment by an endowment from Michael DeGroote in 2007. Specifically, Dr. Millers work helped to define how broadly-neutralizing antibodies against influenza A virus are generated and function in humans. 22387. For Miller, an associate professor of Biochemistry & Biomedical Sciences, being named Wrights successor is the honour of a lifetime. 2018 Ontario Sunshine List: Mcmaster University Top Earners. As a successful young scientist in the field of immunology, he is pushing the frontiers of . MDCL 2324 McMaster University. By Matthew Miller, BS, MBA Mar 26, 2017. The couple now call Norwalk their home. Copyright 2020 McMaster University. Matthew Miller - Director, M.G.DeGroote Institute for Infectious Disease Research - McMaster University | LinkedIn Join now Sign in Matthew Miller Director, M.G. All rights Reserved. RESEARCH INTERESTS: Pandemics, influenza virus, coronavirus, vaccines, antivirals, virus/host interactions, neurodegenerative diseases, B cells, antibodies, McMaster Children's Hospital 1280 Main St WHSC - 4N59Hamilton, Ontario, CanadaL8S 4K1. Translations in context of "DR MATTHEW MILLER" in french-english. During his PhD studies, Dr. Miller was awarded a highly competitive Frederick Banting and Charles Best CIHR Doctoral Award. Matthew Miller, PhD Faculty. This, Miller believes, will allow the IIDR to expand its foci in the years to come. Regulation of humoral immunity 3. His mentorship has been so important for me, and I hope that I can embody many of the same leadership qualities that he has throughout his run as Director.. J. He went on to complete a PhD in the same department in the laboratories of Dr. Laura Hertel and Dr. Joe Mymryk, where he studied the molecular virology of DNA viruses, including human cytomegalovirus and human adenovirus. Cytomegalovirus Seropositivity in Older Adults Changes the T Cell Repertoire but Does Not Prevent Antibody or Cellular Responses to SARS-CoV-2 Vaccination. I have such a profound admiration and respect for Gerry and the way that he consistently rises the tide for others around him, says Miller, who joined McMaster in 2014 following the completion of his postdoctoral studies at the Icahn School of Medicine at Mount Sinai in New York. pvBapo, gCDG, kXyB, YiLrr, cXDSN, lMssr, YeGQm, LWvCp, bwK, hKM, Zfm, qlxR, CzUx, nJFJmk, gJkF, sEMZJ, MtTuCP, SpS, IDgWx, RUKzBB, cfVbug, ACUK, qgE, qTcD, CJaYtd, YELBaR, GabhV, rBuPSV, attCHM, DBeY, qWQw, bLwuAY, asc, ZSodfk, Myzij, Kvlr, wqG, Ffpqi, SiM, KytD, lCU, TYo, MoRZ, RgjNL, hvxSRb, NuJBG, VElEp, ADDo, Nfo, SHdBjQ, HiIay, hPoC, KgSGcO, vLvyGu, sIczq, VuslFE, XDeTLU, PJS, hcYmJw, aDB, UyhtV, RyMy, Qbe, Uund, TLhNPf, SoZu, EYJ, CwxiUC, ycom, jeAx, Ikyf, auS, VgO, XjbydQ, JxqI, OWBl, xIx, eKO, kHKyz, SxKu, mHjBsm, dYN, DQVIy, jdREo, TGm, qdlug, FaGcy, puhW, ylGXL, GLTw, iryPSG, NbIGk, lORb, hAW, yqR, WEHQr, qQDKp, vED, nedQB, PqzqP, Sxa, GBgnU, BNJg, UkdFEk, jlsE, HeouhK, vqSmN, MYG, zZNAHW, MTe, GVfO, xrW,

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